SKU: AFG-HZM-132

AffiGEN® double-stranded RNA (dsRNA) ELISA Assay Kit

Vendor AffiGEN
Regular price €800,00 EUR
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AffiGEN® double-stranded RNA (dsRNA) ELISA Assay Kit

The AffiGEN® double-stranded RNA (dsRNA) ELISA Assay Kit is designed to help detect and measure double-stranded RNA (dsRNA) impurities in mRNA drug products. It's crucial for making sure mRNA vaccines and therapies are safe and effective. dsRNA impurities can reduce the effectiveness of these products and cause unwanted immune reactions. This kit is useful for both early research and large-scale production, providing accurate and sensitive results. Easy to use and highly reliable, the dsRNA ELISA Kit ensures the high quality of mRNA-based drugs by keeping them free from harmful dsRNA impurities.

Key Features of AffiGEN® double-stranded RNA (dsRNA) ELISA Assay Kit

  • Super Sensitive: Detects even tiny amounts of dsRNA, as low as 0.001 pg/μL.
    Very Accurate: Uses high-quality standards to give precise measurements.
  • Highly Specific: Only detects dsRNA, not other types of RNA or DNA.
  • Easy to Use: Comes with ready-made plates, no need for extra prep work.
    Versatile: Works with different standards for various applications.

Applications of AffiGEN® double-stranded RNA (dsRNA) ELISA Assay Kit

mRNA Vaccine Development

  • Quality Assurance: Ensures the purity of mRNA vaccines by detecting and removing dsRNA impurities, which can reduce vaccine effectiveness and trigger unwanted immune responses.
  • Regulatory Compliance: Meets stringent regulatory standards for vaccine development by providing reliable data on dsRNA levels.

Therapeutic mRNA Production

  • Consistency: Monitors dsRNA levels to maintain consistent quality in therapeutic mRNA products.
  • Safety: Ensures therapeutic mRNA does not contain harmful dsRNA impurities, enhancing patient safety.

Research and Development

  • Effectiveness Studies: Helps researchers study the impact of dsRNA impurities on mRNA stability and functionality.
  • Process Optimization: Assists in optimizing purification processes to minimize dsRNA contamination during mRNA production.

Manufacturing Quality Control

  • Batch Testing: Used in routine testing of mRNA batches to ensure they meet quality standards before release.
  • In-process Monitoring: Allows for real-time monitoring of dsRNA levels during the manufacturing process, ensuring ongoing quality control.

Diagnostic Applications

  • Infection Monitoring: Can be used in diagnostic tests to detect dsRNA, which may be indicative of viral infections or other conditions.
  • Biomarker Research: Supports research into dsRNA as a potential biomarker for various diseases.

Academic Research

  • Basic Science: Aids in the study of dsRNA's role in biological processes and its effects on cellular functions.
  • Tool for Teaching: Provides a practical example of ELISA technology for educational purposes in molecular biology courses.