AffiGEN® LNP Kit for Fast in vivo RNA Delivery
The AffiGEN® LNP Kit for Fast in vivo RNA Delivery is a state-of-the-art, ready-to-use lipid nanoparticle (LNP) encapsulation solution. This innovative product is specifically crafted for efficient in vivo RNA delivery in experimental animals. Utilizing a unique endocytosis delivery and endosomal escape mechanism, the AffiGEN® LNP Kit ensures highly effective delivery of various RNAs, including mRNAs, gRNAs, and saRNAs.
Applications of AffiGEN® LNP Kit for Fast in vivo RNA Delivery
- Gene Editing Efficiency Analysis: Enables precise evaluation of gene editing techniques in living organisms.
- Fast in vivo RNA Candidate Evaluation: Accelerates the testing of new RNA sequences in animal models.
- mRNA Vaccine and Drug Development: Facilitates the rapid development and testing of RNA-based vaccines and therapeutics.
- Immune Response Stimulation: Ideal for antibody preparation and studying immune responses.
- High-throughput Screening: Supports large-scale screening of RNA sequences in vivo.
Key Features of AffiGEN® LNP Kit for Fast in vivo RNA Delivery
- Safe and Secure: High biosafety with ethanol-free components, reducing potential toxicity and side effects.
- Rapid Screening: Significantly shortens the mRNA screening and validation cycle, providing results faster than traditional methods.
- Ready-to-Use: Simple, efficient mixing protocol minimizes sample loss, allowing encapsulation of mRNA as low as 1μg for in vivo experiments.
- Exclusive Formulation: Proprietary lipid and formulation technology eliminates patent issues, ensuring unrestricted use.
- Cost-Effective: Eliminates the need for specialized encapsulation equipment, saving on both equipment and labor costs.
Administration Routes of AffiGEN® LNP Kit for Fast in vivo RNA Delivery
- Intravenous Injection: Ensures systemic distribution, targeting multiple organs efficiently.
- Intramuscular Injection: Suitable for localized delivery and sustained release in muscle tissue.
- Intraperitoneal Injection: Ideal for widespread abdominal distribution.
- Subcutaneous Injection: Provides a slow, sustained release and localized targeting.
Advantages of AffiGEN® LNP Kit for Fast in vivo RNA Delivery
- High Targeting Efficiency: Demonstrates comparable targeting effects to microfluidic encapsulated LNPs in liver and spleen tissues.
- Multi-Mode Compatibility: Compatible with various administration routes, offering flexibility in experimental design.
- Time-Saving Protocol: The one-step solution allows for rapid encapsulation and injection, streamlining the workflow.
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Stable and Robust: The formulation is stable under different storage conditions, maintaining efficacy over time.
Technical Specifications of AffiGEN® LNP Kit for Fast in vivo RNA Delivery
- LNP Concentration: Optimized for high efficiency in RNA delivery.
- Particle Size: Uniform and consistent particle size for predictable performance.
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Storage Conditions: Stable at 4°C; avoid freezing.