AffiGEN Blog News | AffiGEN Inc.
-
What is rAAV? A Comprehensive Guide to Recombinant Adeno-Associated Virus
What is rAAV? A Comprehensive Guide to Recombinant Adeno-Associated Virus Recombinant adeno-associated virus (rAAV) is a modified version of the naturally occurring adeno-associated virus (AAV), which scientists use to deliver... -
CRISPR and Gene Editing Technologies
CRISPR and Gene Editing Technologies CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) technology has revolutionized genetics and biotechnology, allowing precise, efficient, and flexible genome editing. Below is an exploration of... -
What are the primary technical challenges in scaling up the production of brain organoids?
What are the primary technical challenges in scaling up the production of brain organoids? Scaling the production of brain organoids faces several key challenges, spanning technical, biological, and ethical domains.... -
Can brain organoids sufficiently model the aging brain?
Brain Organoids as Models: Advantages and Limitations Recapitulation of Developmental Processes Brain organoids derived from human pluripotent stem cells (hPSCs) can recapitulate early developmental processes, such as neurogenesis, gliogenesis, and... -
Are there any industry collaborations using organoids to evaluate the effectiveness of drugs in development?
Are there any industry collaborations using organoids to evaluate the effectiveness of drugs in development? There are several collaborations between academia, industry, and research organizations that are utilizing organoids to... -
What are the critical factors involved in the differentiation of pluripotent stem cells into brain organoids?
What are the critical factors involved in the differentiation of pluripotent stem cells into brain organoids? Differentiation of pluripotent stem cells (PSCs) into brain organoids involves several critical factors and... -
Did studies investigating mutation-specific neuroinflammatory phenotypes include the role of microglia?
Did studies investigating mutation-specific neuroinflammatory phenotypes include the role of microglia? Studies examining mutation-specific neuroinflammatory phenotypes, particularly involving microglia, delve deeply into the cellular and molecular mechanisms. Here’s a more... -
Does microglia remain within organoids during extended culture periods, or do they gradually diminish over time?
Does microglia remain within organoids during extended culture periods, or do they gradually diminish over time? Microglia, the resident macrophages of the central nervous system (CNS), play critical roles in... -
Is it beneficial to incorporate functional neuronal outputs, such as those in nigro-striatal assembloids, into neurological research models?
Is it beneficial to incorporate functional neuronal outputs, such as those in nigro-striatal assembloids, into neurological research models? The development of nigro-striatal assembloids, which simulate the interaction between the substantia... -
Are the microglial cells generated from the same patient?
Are the microglial cells generated from the same patient? Generating microglial cells from a patient involves several intricate steps, combining advanced cellular and molecular biology techniques. Here’s a more detailed... -
At what stage of development can astrocytes be observed in midbrain organoids?
At what stage of development can astrocytes be observed in midbrain organoids? To provide a more technical and detailed explanation of the appearance of astrocytes in midbrain organoids, it's important... -
Comprehensive Overview of Polyamines
Polyamines are small organic cations that are ubiquitous in living organisms. They play crucial roles in cellular functions such as growth, differentiation, and apoptosis. This article provides an exhaustive overview of polyamines, covering their chemical structure, biosynthesis, metabolism, biological functions, roles in health and disease, research applications, and future directions.
