AffiGEN Blog News | AffiGEN Inc.

In the battle against the COVID-19 pandemic, accurate and reliable PCR testing is of utmost importance. One critical aspect that ensures the quality and validity of PCR results is the use of SARS-CoV-2 PCR run controls. These controls serve as reference materials that mimic the genetic material of the virus, allowing laboratories to monitor and validate the performance of their PCR assays.

By including SARS-CoV-2 PCR run controls in each testing run, laboratories can assess the efficiency and sensitivity of their PCR methods, detect potential issues, and ensure the accuracy of test results. These controls contain specific target sequences that match those found in the SARS-CoV-2 genome, enabling laboratories to verify the amplification and detection steps of the PCR process.

Furthermore, SARS-CoV-2 PCR run controls play a crucial role in evaluating the overall performance of the testing workflow. They help identify any variations or inconsistencies that may arise from sample collection, RNA extraction, reverse transcription, or PCR amplification. By monitoring the run controls alongside patient samples, laboratories can confidently interpret PCR results and distinguish between true positive, true negative, and invalid results.

The availability of high-quality SARS-CoV-2 PCR run controls from reputable manufacturers is essential for laboratories to conduct accurate and reliable testing. These controls should be designed to closely mimic the target sequences of the SARS-CoV-2 virus and exhibit stability, consistency, and compatibility with various PCR platforms. Regular use of these controls allows laboratories to maintain the highest standards in their testing procedures and ensure the integrity of COVID-19 diagnostic results.

In conclusion, the incorporation of SARS-CoV-2 PCR run controls is paramount in achieving accurate and trustworthy PCR testing for COVID-19. By implementing a comprehensive quality control strategy that includes these controls, laboratories can confidently diagnose infections, monitor disease prevalence, and contribute to effective public health interventions.